Endocrine Abstracts

Objective: Mean platelet volume (MPV), is an indicator of platelet sizes, and an indirect marker of platelet function and activity. In this study, we aimed to evaluate MPV in patients with acromegaly, and to investigate the effects of octreotide long acting repeatable (LAR) on MPV after 6-month therapy.Methods: Data of 25 patients with acromegaly (16 women; 9 men; mean age, 43.8±13.5 years) included in the study were searched retrospectively. The da...

Introduction: Left hepatic lobe volume (LHLV) has been associated with hyperinsulinemia and insulin resistance in obese women.Aim: To study the correlation between LHLV and body weight, regardless the weight and gender of the patient.Subjects and methods: The left hepatic lobe was evaluated with an echographic probe of 3.5 MHz. The LHLV (cm3) was calculated with the formula: antero-posterior diameter (length)×longit...

Introduction and aims: Mean platelet volume (MPV) is a newly indicator of platelet activation which was associated with atherosclerosis. There are limited studies in the literature about MPV levels in patients with both hypoparathyroidism and hyperparathyroidism. This preliminary study, we aimed to investigate a relationship with MPV and serum PTH and calcium levels in patients with disorder of calcium metabolism.Materials and methods: Fourty-nine hyperp...

Aim: Re-analyzing the effect of injectable testosterone undecanoat depot (TUD) in hypogonadic patients.Materials & methods: (A) Patients: at onset 191 men with hypogonadism (median age: 64 years). (B) Distribution: by decade. (C) TUD (NebidoR-Bayer-Schering) 1000 mg was injected one per 3 months i.m. (D) Prostate volume (PV) by per-abdominal ultrasound: 3.5 MHz probe, elliptical volume (cm3), Aloka 550. (E). Time of analysis: be...

Dopamine agonists have been used as first or adjunctive therapy for acromegaly for many years, but relatively few studies have assessed the efficacy of a newer agonist, cabergoline (CAB) alone or in combination with somatostatin analogues (SSA). The aim of this study was to evaluate the efficacy of combined treatment with SSA plus CAB in patients with acromegaly and resistance to SSA, defined as lack of normalization of IGF-I levels after long-term (>1 year) and hig...

Introduction: PTC patients with lymph node (LN) metastases of greater volume (in>5 LN and/or with larger metastases >5mm, hereinafter N1>5) usually receive radioiodine (RAI). Some guidelines suggest carrying out an evaluation of the response to surgical treatment (RST), recommending lower RAI dose (activity) in patients with good RST.Objectives: a)To evaluate the RST in patients with PTC and N1>5 b)To evaluate the disease-free-survival (D...

Aim: To study features of neuroendocrine, hormonal and ophthalmic complications of giant pituitary adenomas depending on the volume and growth of the tumor (data from a prospective study).Material and methods: Us for the period from 2020 to 2022. 151 patients with macro- and giant NFPA were prospectively examined. According to the size of pituitary adenomas, patients of prospective (151 patients) observation were divided into 2 groups: group 1 – pat...

Background: Parathyroid hormone (PTH) is a key regulator of mineral metabolism, the homeostasis of calcium, phospate, vitamin D and bone turnover. Hypoparathyroidism is a rare disease characterized by hypocalceamia with inappropriately low plasma levels of PTH. Mean platelet volume (MPV) is the measure of platelet size. Increased MPV has been associated with cardiovascular risk.Objective: In our preliminary study, we aim to show that untreated hypoparath...

Objective: Hashimoto’s thyroiditis (HT) is extremely common, particularly among women. Mean platelet volume (MPV) and platelet distribution width (PDW) are the measure of platelet size. We aimed to investigate MPV and PDW levels in euthyroid woman with HT.Methods: This was a retrospective study in which the data were obtained from a computerized patient registry database. We evaluated 145 women with HT and 60 matched healty controls, who applied to ...

Goiter prevalence (GP) and median UIC in population studies are both considered markers of iodine nutrition. Controversy exists which of them is more reliable.Aim: To assess correlation between UIC and thyroid volume in Polish schoolchildren.Material and methods: 9402 Polish schoolchildren (51.3% girls, 48.7% boys) aged 6–12 years were examined in 1999–2011 (‘Thyromobil’ action). 40.9% of children were born at l...